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Inflammatory response, immunosuppression, and cancer recurrence after perioperative blood transfusions  J.P. Cata, H. Wang, V. Gottumukkala, J. Reuben,

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Presentation on theme: "Inflammatory response, immunosuppression, and cancer recurrence after perioperative blood transfusions  J.P. Cata, H. Wang, V. Gottumukkala, J. Reuben,"— Presentation transcript:

1 Inflammatory response, immunosuppression, and cancer recurrence after perioperative blood transfusions  J.P. Cata, H. Wang, V. Gottumukkala, J. Reuben, D.I. Sessler  British Journal of Anaesthesia  Volume 110, Issue 5, Pages (May 2013) DOI: /bja/aet068 Copyright © 2013 The Author(s) Terms and Conditions

2 Fig 1 The figure illustrates the interaction between cellular and humoral responses against cancer cells. The cellular immune response is composed of Th1 and Tc1 (anti-tumour) and Th2 and Tc2 (pro-tumoral) lymphocytes. Similarly, the cytokine immune response is accomplished by Th1 (IL-2, IL-12, IFN-γ, and TNF-γ) predominantly antitumour cytokines; in contrast, the Th2 cytokines (IL-4, IL-5, IL-6, and IL-10) have mainly pro-tumour actions. British Journal of Anaesthesia  , DOI: ( /bja/aet068) Copyright © 2013 The Author(s) Terms and Conditions


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