1. Synergistic Immunosuppression Caused by High-Dose Methylprednisolone and Cardiopulmonary Bypass 
Hisanori Mayumi, MD, Qui-Wei Zhang, MD, Atsuhiro Nakashima, MD, Munetaka Masuda, MD, Hiroyuki Kohno, MD, Yoshito Kawachi, MD, Hisataka Yasui, MD 
The Annals of Thoracic Surgery 
Volume 63, Issue 1, Pages (January 1997)
DOI: /S (96)

2. Fig. 1
Changes in (a) white blood cell count, (b) lymphocyte count, (c) C-reactive protein level, and (d) body weight. (Ad. = admission; C-group = control group; CPB = cardiopulmonary bypass; POD = postoperative day; S-group = steroid group; ∗p < 0.05 by Student’s t test between groups; ∗∗p < 0.01 by t test; ∗∗∗p < by t test.)
The Annals of Thoracic Surgery  , DOI: ( /S (96) )

3. Fig. 2
Changes in (a) CD3+ (T) cells, (b) CD20+(B) cells, and (c) CD16+(NK) cells. (Ad. = admission; C-group = control group; CPB = cardiopulmonary bypass; POD = postoperative day; S-group = steroid group; ∗p < 0.05 by Student’s t test between groups; ∗∗p < 0.01 by t test.)
The Annals of Thoracic Surgery  , DOI: ( /S (96) )

4. Fig. 3
Changes in (a) CD4+ (helper/inducer T) cells, (b) CD8+ (killer/suppressor T) cells, and (c) CD4/CD8 ratio. (Ad. = admission; C-group = control group; CPB = cardiopulmonary bypass; POD = postoperative day; S-group = steroid group; ∗p < 0.05 by Student’s t test between groups; ∗∗p < 0.01 by t test.)
The Annals of Thoracic Surgery  , DOI: ( /S (96) )

5. Fig. 4
Changes in (a) phytohemagglutinin (PHA) response, (b) interleukin-2 (IL-2) production, and (c) natural killer (NK) cell activity. (Ad. = admission; C-group = control group; CPB = cardiopulmonary bypass; POD = postoperative day; S-group = steroid group; spont. = spontaneous release; ∗p < 0.05 by Student’s t test between groups; ∗∗p < 0.01 by t test; ∗∗∗p < by t test.)
The Annals of Thoracic Surgery  , DOI: ( /S (96) )

6. Fig. 5
Hemodynamics and pulmonary function: (a) cardiac index and (b) arterial oxygen tension (PaO2) under pure oxygen. (CPB = cardiopulmonary bypass; C-group = control group; FiO2 = inspired oxygen fraction; POD = postoperative day; S-group = steroid group.)
The Annals of Thoracic Surgery  , DOI: ( /S (96) )

7. Fig. 6
Metabolism during operations: (a) lactate and (b) serum glucose levels. (C-group = control group; CPB = cardiopulmonary bypass; Max. = maximum; op. = operation; S-group = steroid group; ∗p < 0.05 by Student’s t test between groups; ∗∗p < 0.01 by t test.)
The Annals of Thoracic Surgery  , DOI: ( /S (96) )