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Volume 32, Issue 3, Pages (November 2001)

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Presentation on theme: "Volume 32, Issue 3, Pages (November 2001)"— Presentation transcript:

1 Volume 32, Issue 3, Pages 376-378 (November 2001)
Glutamate and GABA  Amy B MacDermott  Neuron  Volume 32, Issue 3, Pages (November 2001) DOI: /S (01)

2 Figure 1 Activation of Kainate Receptors Indirectly Depresses GABA Release from Dorsal Horn Neurons Glutamate activates a presynaptic kainate receptor (KAR) causing enhanced action potential-independent GABA release by depolarization-induced opening of voltage-gated Ca2+ channels (VGCC). The GABA binds to postsynaptic GABAA receptors as well as presynaptic GABAB receptors. The action on presynaptic GABAB receptors depresses action potential-dependent GABA release Neuron  , DOI: ( /S (01) )

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