1. VOD/SOS: Aligned Education for Patients and the Interprofessional Team

3. Overview

4. Case 1 Presentation

5. Risk Factors for VOD

6. Risk Factors for VOD (cont)

7. Case 1 Presentation (cont)

8. Case 1 Presentation (cont)

9. Case 1 Presentation (cont)

10. Importance of Early Recognition of VOD

11. Signs and Symptoms to Monitor for

12. Baltimore Criteria

13. Modified Seattle Criteria

14. New EBMT Criteria for Severity Grading of Suspected SOS/VOD in Adults

15. Case 1 Presentation (cont)

16. Next Steps

17. Contraindications to Defibrotide Therapy

18. Defibrotide Phase 3 Trial Design

19. Defibrotide Phase 3 Trial Results

20. AEs Associated With Defibrotide in the International Compassionate Use Program

21. Defibrotide for VOD Pooled Analysis of Survival Reported at ASH 2018

22. Analysis 1: Before/After Specific Days

23. Analysis 2: On Specific Days

24. AEs With Defibrotide Use

25. Supportive Measures

26. Other Supportive Measures

27. Case 1 Conclusion

28. Case 2 Presentation

29. Case 2 Presentation (cont)

30. Case 2 Presentation (cont)

31. Key Take-Aways

32. Abbreviations