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When less is more: Go slowly when repopulating a decellularized valve in vivo!
Christof Stamm, MD, Gustav Steinhoff, MD The Journal of Thoracic and Cardiovascular Surgery Volume 132, Issue 3, Pages (September 2006) DOI: /j.jtcvs Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions
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Figure 1 A, Decellularized porcine heart valve impregnated with biodegradable poly(hydroxy)butyrate to reduce xenoreactivity and improve hemocompatibility and mechanical performance for a limited time. B, Note that polymer impregnation process preserves porosity of decellularized ECM scaffold, so that repopulation with host cells is not disturbed. The Journal of Thoracic and Cardiovascular Surgery , DOI: ( /j.jtcvs ) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions
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