1. FMD VP1-specific IgG, IgG1, and IgG2 in sera of guinea pigs (n = 6/group) immunized on days 1 and 21 by intramuscular injection of FMDV antigens (type O) in saline with (group 1) or without (group 4) ECMS (100 μg) or in oil emulsion with (group 2) or without (group 3) ECMS (100 μg).
FMD VP1-specific IgG, IgG1, and IgG2 in sera of guinea pigs (n = 6/group) immunized on days 1 and 21 by intramuscular injection of FMDV antigens (type O) in saline with (group 1) or without (group 4) ECMS (100 μg) or in oil emulsion with (group 2) or without (group 3) ECMS (100 μg). Group 5 was a control without any injection. FMD VP1-specific IgG and subclasses in the serum collected 4 weeks after the boosting injection were measured by indirect double antibody sandwich ELISA as described in the text. The values are expressed as means ± SD (n = 6). Bars with different letters are statistically significantly different (P < 0.05). OD, optical density.
Chenwen Xiao et al. Clin. Vaccine Immunol. 2007; doi: /CVI