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Efren Rael, MD, FAAAAI  Journal of Allergy and Clinical Immunology 

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Presentation on theme: "Efren Rael, MD, FAAAAI  Journal of Allergy and Clinical Immunology "— Presentation transcript:

1 Unraveling the complexity of leukotriene and prostaglandin inflammatory signaling 
Efren Rael, MD, FAAAAI  Journal of Allergy and Clinical Immunology  Volume 137, Issue 1, Pages (January 2016) DOI: /j.jaci Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Synergy: mast cell activation, vascular inflammation through CysLT1R, and EP3. BLT, Leukotriene B4 receptor; FLAP, 5-lipoxygenase activating protein; HPETE, 5-hydroperoxyeicosatetraenoic acid; 5-LO, 5-lipoxygenase; LTC4S, leukotriene C4 synthase; PGDS, prostaglandin D2 synthase; PGES, prostaglandin E synthase; PGF2α, prostaglandin F2α; PGH2 9-11KR, prostaglandin H endoperoxide reductase; PKG, protein kinase G; TXA2, thromboxane A2. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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