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Characterization of the early pharmacodynamic profile of oral methadone for cancer- related breakthrough pain: a pilot study  Kim Fisher, PhD, Carla Stiles,

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Presentation on theme: "Characterization of the early pharmacodynamic profile of oral methadone for cancer- related breakthrough pain: a pilot study  Kim Fisher, PhD, Carla Stiles,"— Presentation transcript:

1 Characterization of the early pharmacodynamic profile of oral methadone for cancer- related breakthrough pain: a pilot study  Kim Fisher, PhD, Carla Stiles, RN, Neil A. Hagen, MD, FRCPC (Neurology)  Journal of Pain and Symptom Management  Volume 28, Issue 6, Pages (December 2004) DOI: /j.jpainsymman Copyright © 2004 U.S. Cancer Pain Relief Committee Terms and Conditions

2 Fig. 1 Mean changes in pain intensity from baseline across time, measured by numeric rating scale (0=no pain, 10=worst pain possible) completed at 10-minute intervals following treatment with patients' usual ‘rescue’ opioid or optimal dose of oral methadone HCl. Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman ) Copyright © 2004 U.S. Cancer Pain Relief Committee Terms and Conditions

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