1. ‘Endocrine NAFLD’ a hormonocentric perspective of nonalcoholic fatty liver disease pathogenesis 
Amedeo Lonardo, Cesare Carani, Nicola Carulli, Paola Loria 
Journal of Hepatology 
Volume 44, Issue 6, Pages (June 2006)
DOI: /j.jhep
Copyright © 2006 European Association for the Study of the Liver Terms and Conditions

2. Fig. 1
The ‘Endocrine NAFLD’. The figure illustrates the endocrine organs (left column) involved and respective major derangements (right column) consistently reported in NAFLD. GH, growth hormone; IGF-I, insulin-like growth factor-I; RAAS, renin angiotensin aldosterone system; ASP, acylation stimulating protein; SHBG, sex hormone binding globulin.
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2006 European Association for the Study of the Liver Terms and Conditions

3. Fig. 2
Estrogen replacement reverses steatosis in male mice and humans with estrogen-deficiency. Liver biopsy in male ArKO (aromatase knockout) mouse (left panels) and in a male patient with congenital aromatase deficiency (right panels) before and after estrogen replacement. Modified from Hewitt KN, et al. [94] and Maffei L, et al. [103], with permission.
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2006 European Association for the Study of the Liver Terms and Conditions

4. Fig. 3
Putative relationship between derangements of hormones/cytokines (visceral) obesity and NAFLD. Hormonal derangements can be primarily responsible for the development of NAFLD via anthropometric changes and/or alterations in the homeostasis of energy and metabolism of glucose and lipids.
Journal of Hepatology  , DOI: ( /j.jhep )
Copyright © 2006 European Association for the Study of the Liver Terms and Conditions