Presentation is loading. Please wait.

Presentation is loading. Please wait.

Growth hormone, insulin-like growth factor I, and leptin interaction in human cultured lutein granulosa cells steroidogenesis  Maria Karamouti, M.D, Panagoula.

Similar presentations


Presentation on theme: "Growth hormone, insulin-like growth factor I, and leptin interaction in human cultured lutein granulosa cells steroidogenesis  Maria Karamouti, M.D, Panagoula."— Presentation transcript:

1 Growth hormone, insulin-like growth factor I, and leptin interaction in human cultured lutein granulosa cells steroidogenesis  Maria Karamouti, M.D, Panagoula Kollia, Ph.D., Athanasios Kallitsaris, M.D., Nikolaos Vamvakopoulos, Ph.D., Georgios Kollios, Ph.D., Ioannis E. Messinis, M.D., Ph.D.  Fertility and Sterility  Volume 90, Issue 4, Pages (October 2008) DOI: /j.fertnstert Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Effect of leptin in different doses on (A) E2 and (B) P synthesis by human luteinized granulosa cells after 24 and 72 hours of culture. Data are in mean ± SEM. Each column shows results of 20 cultures from 20 different women. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Effect of growth hormone (GH; 100 ng/mL), insulin-like growth factor I (IGF-I; 30 ng/mL), and their combination on (A) E2 and (B) P synthesis by human luteinized granulosa cells after 24 and 72 hours of culture. Data are in mean ± SEM. Each column shows results of 20 cultures from 20 different women. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

4 Figure 3 Estradiol (A,C,E) and P (B,D,F) production by human luteinized granulosa cells after 24 and 72 hours of culture with GH (growth hormone), IGF-I (insulin-like growth factor-I), or GH+IGF-I in the absence or the presence of leptin at the doses of 1, 10, and 100 ng/mL. Data are in mean ± SEM. Each column shows results of 20 cultures from 20 different women. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions


Download ppt "Growth hormone, insulin-like growth factor I, and leptin interaction in human cultured lutein granulosa cells steroidogenesis  Maria Karamouti, M.D, Panagoula."

Similar presentations


Ads by Google