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Sequential versus Monophasic Media Impact Trial (SuMMIT): a paired randomized controlled trial comparing a sequential media system to a monophasic medium 

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Presentation on theme: "Sequential versus Monophasic Media Impact Trial (SuMMIT): a paired randomized controlled trial comparing a sequential media system to a monophasic medium "— Presentation transcript:

1 Sequential versus Monophasic Media Impact Trial (SuMMIT): a paired randomized controlled trial comparing a sequential media system to a monophasic medium  Marie D. Werner, M.D., Kathleen H. Hong, M.D., Jason M. Franasiak, M.D., Eric J. Forman, M.D., H.C.L.D., Christine V. Reda, B.S.N., R.N., Thomas A. Molinaro, M.D., M.S.C.E., Kathleen M. Upham, B.S., Richard T. Scott, M.D., H.C.L.D.  Fertility and Sterility  Volume 105, Issue 5, Pages (May 2016) DOI: /j.fertnstert Copyright © 2016 The Authors Terms and Conditions

2 Figure 1 Experimental design. Retrieved zygotes for each patient were split into two groups and cultured in sequential or monophasic media. Embryological developmental outcomes and rates of implantation resulting in a live birth were compared. CCS = comprehensive chromosome screening; ICSI = intracytoplasmic sperm injection. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2016 The Authors Terms and Conditions

3 Figure 2 Paired analysis of usable blastulation rate favors sequential media. Of 192 patients, 97 were likely to have more embryos develop into usable blastocysts when cultured in sequential media. P=.0001. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2016 The Authors Terms and Conditions


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