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The first successful paternity through in vitro fertilization–intracytoplasmic sperm injection with a man homozygous for the 5α-reductase-2 gene mutation 

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Presentation on theme: "The first successful paternity through in vitro fertilization–intracytoplasmic sperm injection with a man homozygous for the 5α-reductase-2 gene mutation "— Presentation transcript:

1 The first successful paternity through in vitro fertilization–intracytoplasmic sperm injection with a man homozygous for the 5α-reductase-2 gene mutation  Hey-Joo Kang, M.D., Julianne Imperato-McGinley, M.D., Yuan-Shan Zhu, B.M., Ph.D., Li-Qun Cai, M.D., Peter Schlegel, M.D., Gianpiero Palermo, M.D., Ph.D., Zev Rosenwaks, M.D.  Fertility and Sterility  Volume 95, Issue 6, Pages 2125.e e8 (May 2011) DOI: /j.fertnstert Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 A representative single-stranded conformational polymorphism (A) and DNA sequencing (B) analysis of exon 5 of the 5α-reductase-2 gene in the subjects. Arrows in B indicate the replacement of cytosine (C) in the normal subject by thymidine (T) in the patient. In A: N = normal; P = patient; C = carrier; M = mother. Fertility and Sterility  , 2125.e e8DOI: ( /j.fertnstert ) Copyright © 2011 American Society for Reproductive Medicine Terms and Conditions

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