1. Is oocyte meiotic spindle morphology associated with embryo ploidy
Is oocyte meiotic spindle morphology associated with embryo ploidy? A prospective cohort study 
Liza Tilia, B.Sc., Christos Venetis, Ph.D., Suha Kilani, Ph.D., Simon Cooke, Ph.D., Michael Chapman, M.B.B.S., M.D. 
Fertility and Sterility 
Volume 105, Issue 4, Pages e7 (April 2016)
DOI: /j.fertnstert
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Study flow chart. Patients (n = 132) underwent PGS/D and PLM. Only patients with embryos biopsied on day 3 with conclusive results (n = 113) were included in the primary analysis.
Fertility and Sterility  , e7DOI: ( /j.fertnstert )
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
Polarized light microscopy images of the various types of oocyte meiotic spindles. (A) Normal, (B), dysmorphic, (C) telophase, (D) translucent, (E) no visible spindle.
Fertility and Sterility  , e7DOI: ( /j.fertnstert )
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

4. Supplemental Figure 1
Receiver operator characteristics analyses of the capacity of embryo morphology alone and embryo morphology with spindle morphology to predict euploidy. Morphology as assessed on day 5.
Fertility and Sterility  , e7DOI: ( /j.fertnstert )
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions

5. Supplemental Figure 2
Euploidy rates according to spindle morphology and day-5 embryo quality. Error bars = 95 confidence interval.
Fertility and Sterility  , e7DOI: ( /j.fertnstert )
Copyright © 2016 American Society for Reproductive Medicine Terms and Conditions