1. CHEAR (Child Health Environmental Assessment Resource) Ontology
Team Members: Yue Liu (Robin) Zhicheng Liang (Jason) Anirudh Prabhu John Sheehan
Week 8 - Progress Report

2. Recent Ontology Changes - TemporalEntity
Class TemporalEntity was added with 2
subclasses:
- Instant Interval
Data Properties
months, years, weeks etc. for set values
for the duration.
Exact dates and times for events.
Using this we can infer age or duration
between 2 instants.
Using the time ontology helps us create a timeline.
Add new class survey data for date id profile
Study hasResource min 1 DataCollectionInstrument
Study ≡ ⩾1 hasResource.DataCollectionInstrument
DataCollectionInstrument hasContent min 1 Question
DataCollectionInstrument ≡ ⩾1 hasContent.Question
StudyPerson conducts min 1 Study
StudyPerson ≡ ⩾1 conducts.Study
Patient hasProfile exactly 1 PatientProfile
Patient ≡ =1 hasProfile.PatientProfile

3. Recent Ontology Changes - TemporalEntity
Instant is an interval with zero time, so beginning and end are the same. There are properties hasBeginning and hasEnd. Proper intervals are ones whose beginning and end are different. It can be specified as: :ProperInterval a owl:Class ; rdfs:subClassOf :Interval ; owl:disjointWith :Instant . The DurationDescription class contains the duration of an interval. An interval can be 1 day 2 hours, or 26 hours, or 1560 minutes, and so on.

4. Recent Ontology Changes - Response Type
Mark Fox’s survey ontology has been integrated by taking use of their response classes.
Response is the superclass of all response types.
A subclass defines the list of possible responses that are presented to the interviewee.
The property rdfs:Label which is the string that appears as the selection. dc:Description provides a description of the response/individual if more explanation is required.
New response types can be easily added to the ontology by adding a subclass to Response.

5. New Competency Question #1
For a 4 year old child, what could be some of the typical causes of physician diagnosed asthma? Answer : Some of the causes of asthma for a 4 year old children would include, passive smoking, maternal stress during pregnancy, or allergies. How the Ontology is used : Age is either provided by the user or determined using the time ontology properties based on the inference. If the either is not directly provided, then the date of birth is used as the beginning date (using the hasBeginning property) and the end date is set as the date is of the study. Using the durationdescription class we can calculate the duration of any interval. Once we have the age of the child participating in the study, we look at the age range for the different studies being compared. And we provided the answer based on the hasPositiveRelation based on the information encoded in the ontology.

6. New Competency Question #2
What is the difference in approach among the two studies “Measures of Obesity Associated with Asthma Diagnosis in Ethnic Minority Children” and “Prenatal and postnatal stress and wheeze in Mexican children Sex-specific differences” in determining the socioeconomic status of the participants of the study ?
Answer : While asking for the Education Level and Income of the family member is common to both studies, the “Prenatal and postnatal stress and wheeze in Mexican children Sex-specific differences” study goes in more detail, asking questions about the kind of house the participant’s family owns, the number of cars they have, what kind of gadgets they use in their house etc.

7. New Competency Question #2
How the Ontology is used: The Ontology encodes the whole question as it is, these encoded questions should be mapped to subjects using the hasSubject property. Subjects of questions from different studies can be compared to each other to find the details of the questions asked. For the above question, we first access the “Socio Economic” questions from both studies. We then compare the subjects of the questions, which have been encoded as concepts and mapped using "hasSubject", in these questions, both studies have questions with subjects like Education Level and Income. So we know they are similar. Questions that have completely different subjects can be used to answer the question for the difference in approach.

8. New Competency Question #3
In the questionnaires about asthma symptoms in “Measures of Obesity Associated with Asthma Diagnosis in Ethnic Minority Children” and “Measures of obesity associated with asthma diagnosis in ethnic minority children”, what other terms are used to represent “Wheezing”? Answer : Whistling is also used to indicate an asthma symptom in a similar fashion to Wheezing. How the Ontology is used : We use the owl:sameAs property (or similar) to link Wheezing and Whistling to show that in this context these individuals have the same meaning across both questionnaires.

9. New Competency Question #4
In the questionnaires about asthma symptoms in “Measures of Obesity Associated with Asthma Diagnosis in Ethnic Minority Children” and “Measures of obesity associated with asthma diagnosis in ethnic minority children”, what other symptoms of asthma are different from “Wheezing”? Answer : Chest Tightness Cough How the Ontology is used : We use the owl:differentFrom property (or similar) to indicate that the symptoms Chest Tightness and Cough are different from Wheezing in both questionnaires.

10. Thank You.

11. CHEAR Ontology (Backup Slide)
Resource for new study questionnaire
Compare different study questionnaire
Body Measure & Calculation
Asthma Symptom Monitoring
Study Questionnaire Encoding
Subjects and Topics
Combing the 2 - enrich for new study builders as resources
Compare the 2 different study questionaire
Next step: