1. Biology 12 Revised Presentation – Jan 2018 Student
DNA Replication
Biology 12
Revised Presentation – Jan 2018
Student

2. DNA Structure - Recap

3. Recap

4. Recap

5. What does this look like in the cell?

6. DNA – Recap

7. When does DNA replication in the cell happen?

8. happens

9. Steps of DNA Replication
When the DNA helix ___________, it exposes the nitrogenous bases
For extra information / notes on this process, watch DNA Structure & Replication, Crash Course Biology video #10 (from 8:52 onwards)
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10. Steps of DNA Replication
Step 2: Complementary Base Pairing
-First, RNA _________ are complementarily paired to the DNA parent strands
-Next, free floating ____________ (always present in the nucleus) move in and complementarily pair up with the exposed nitrogenous bases
- Adenine always binds with Thymine, Guanine always pairs with _________ .
-DNA _________- is used to place and join the new nucleotides to DNA parent strands

11. Steps of DNA Replication
Step 2: Complementary Base Pairing (continued) -DNA polymerase can only read the template DNA in a 3’ to 5’ ________ -DNA can only make a new complementary strand in a 5’ to 3’ direction. -Since DNA strands are oriented in an anti-parallel configuration, new DNA strands are made in two ________ directions.

12. Steps of DNA Replication
Step 2: Complementary Base Pairing (continued) -The leading strand makes a new strand of DNA in a 5’ to 3’ direction (it follows the DNA helicase enzyme, moving up the old or parent strand in a 3’ to 5’ direction.) -The _________ strand makes a new strand of DNA in pieces called Okazaki fragments

13. Steps of DNA Replication
Step 3: Nucleotide Bonding -The new strands of DNA are ___________ up. DNA ligase seals the sugar-____________ backbones and Okazaki fragments of the new daughter strands Step 4: Proof reading -DNA polymerase checks for and corrects mismatched nucleotides and _________ (mutations)

14. The result? of DNA Replication
-Two new DNA molecules are made. Why does your DNA replicate in a semi-conservative fashion?