1. Metformin modulates IL-8, IL-1β, ICAM and IGFBP-1 expression in human endometrial stromal cells 
Ariane Germeyer, Julia Jauckus, Markus Zorn, Bettina Toth, Edison Capp, Thomas Strowitzki 
Reproductive BioMedicine Online 
Volume 22, Issue 4, Pages (April 2011)
DOI: /j.rbmo
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

2. Figure 1
In-vitro effects of metformin during the process of decidualization with oestrogen/progesterone on prolactin production in supernatant of endometrial stromal cells on days 10 and 15 of decidualization. Values represent mean±standard error of the mean. *=P<0.05, paired Student’s t-test.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

3. Figure 2
Gene expression of insulin-like growth factor binding protein 1 (IGFBP-1) after incubation with metformin and insulin. Samples (n=5) were treated either with oestrogen/progesterone alone (control) or with long-term (14day) or short-term (48h) metformin in absence or presence of insulin for 24h. *=P<0.05. Error bars represent standard error of the mean.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

4. Figure 3
Insulin-like growth factor binding protein 1 (IGFBP-1) protein (pg/ml) in supernatant of endometrial stromal cells decidualized with oestrogen/progesterone alone (control) or with long-term (14day) or short-term (48h) metformin in absence or presence of insulin for 24h. *=P<0.01. Error bars represent standard error of the mean.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

5. Figure 4
Gene expression of interleukin (IL) 8 after incubation with metformin and insulin. Samples (n=5) were treated with oestrogen/progesterone alone (control) or with long-term (14day) or short-term (48h) metformin in absence or presence of insulin for 24h. *=P<0.05. Error bars represent standard error of the mean.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions

6. Figure 5
Gene expression of interleukin (IL) 1β with metformin and insulin. Samples (n=5) were treated with oestrogen/progesterone alone (control) or with long-term (14day) or short-term (48h) metformin in absence or presence of insulin. *=P<0.05. Error bars represent standard error of the mean.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo )
Copyright © 2010 Reproductive Healthcare Ltd. Terms and Conditions