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Factor V Leiden mutation: a treatable etiology for sporadic and recurrent pregnancy loss  Charles J. Glueck, M.D., Srikant Gogenini, M.D., Jitender Munjal,

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Presentation on theme: "Factor V Leiden mutation: a treatable etiology for sporadic and recurrent pregnancy loss  Charles J. Glueck, M.D., Srikant Gogenini, M.D., Jitender Munjal,"— Presentation transcript:

1 Factor V Leiden mutation: a treatable etiology for sporadic and recurrent pregnancy loss 
Charles J. Glueck, M.D., Srikant Gogenini, M.D., Jitender Munjal, M.D., Trent Tracy, P.A., Joel Pranikoff, M.D., Ping Wang, Ph.D.  Fertility and Sterility  Volume 89, Issue 2, Pages (February 2008) DOI: /j.fertnstert Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

2 Figure 1 Percentage of women with the factor V Leiden mutation in 141 women with ≥1 pregnancy and 1 pregnancy loss (1 sporadic pregnancy loss), in 638 women with ≥1 pregnancy, ≥1 live birth, and 0 pregnancy loss, and in 44 women with ≥3 pregnancy losses (recurrent pregnancy loss). Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

3 Figure 2 Pregnancy loss at ≤5 weeks (pre-embryonic), >5–9 weeks (embryonic), >9–13 weeks (fetal), >13–26 weeks (second trimester), and >26–36 weeks (third trimester) in 18 women with the factor V Leiden (FVL) mutation and 1 sporadic pregnancy loss, in 9 FVL carriers with recurrent pregnancy loss, and in 35 women negative for the FVL mutation with recurrent pregnancy loss. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions


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