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Intravenous fosfomycin—back to the future

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Presentation on theme: "Intravenous fosfomycin—back to the future"— Presentation transcript:

1 Intravenous fosfomycin—back to the future
Intravenous fosfomycin—back to the future. Systematic review and meta-analysis of the clinical literature  B. Grabein, W. Graninger, J. Rodríguez Baño, A. Dinh, D.B. Liesenfeld  Clinical Microbiology and Infection  Volume 23, Issue 6, Pages (June 2017) DOI: /j.cmi Copyright © 2016 The Authors Terms and Conditions

2 Fig. 1 Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) flowchart describing the search strategy. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2016 The Authors Terms and Conditions

3 Fig. 2 Descriptive summary of the studies reviewed here. (a) Numbers of patients treated with intravenous fosfomycin by treatment indication as per MedDRA version BJI, bone and joint infections; UTI, urinary tract infections; CNS, central nervous system infections; SSTI, skin and soft-tissue infections. (b) Absolute numbers of microbiological isolates reported by pathogen. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2016 The Authors Terms and Conditions

4 Fig. 3 Clinical efficacy in patients who were treated with intravenous fosfomycin compared with other antibiotic agents. Odds ratios (ORs) > 1 indicate increased clinical efficacy with fosfomycin. Diamonds indicate pooled ORs (± 95% CI). Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2016 The Authors Terms and Conditions


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