Download presentation
Presentation is loading. Please wait.
1
The aging ovary—the poor granulosa cells
Carla Tatone, Ph.D., Fernanda Amicarelli, Ph.D. Fertility and Sterility Volume 99, Issue 1, Pages (January 2013) DOI: /j.fertnstert Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions
2
Figure 1 Some of the possible links in the positive feedback loop by which oxidative stress and carbonyl stress promote AGE formation during ovarian follicle aging. Decreased antioxidant and antiglycation defenses along with mitochondrial dysfunctions might be the driving force for the progressive metabolic impairment during aging. Altered glucose metabolism can be an additional factor promoting AGE accumulation. Fertility and Sterility , 12-17DOI: ( /j.fertnstert ) Copyright © 2013 American Society for Reproductive Medicine Terms and Conditions
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.