1. Blood Products
Biology 12

2. Learning Goals I will be able to explain the three main parts of blood
I will be able to explain the clotting process

3. What is in Your Blood? Red blood cells- erythrocytes = red
Thrombocytes - platelets = yellow
Leukocyte - white blood cell = light green
Plasma – fluid (90%) water with dissolved salts and proteins

4. Hemocrit
Gives an estimate of percent of the various parts of your blood
Are you making enough RBC’s?
Do you have more WBC’s? (clue to infection)

5. What is in your Blood?

6. What is Blood Plasma
90% water and dissolved in it… a lot of stuff such as...
Blood proteins
Albumin - osmotic balance (liver)
Fibrinogen - blood clotting (liver)
Gases (O2, HCO3- CO2,)
Nutrients (fats, glucose, amino acids, nucleotides)
Wastes (urea, ammonia)
Vitamins
Hormones
Salts

7. How Do you Make Blood?
Watch video

8. Making New Red Blood Cells
making of new RBC in bone marrow rely on the hormone erthyropoetin being released from the kidney to start the process

9. Positive/Negative Feedback Loop

10. Importance of Bone Marrow
Large bone marrow make new blood cells
Pelvis
Thigh (femur)

11. Blood Clotting
Damage to platelets initiate clotting reaction (ie: impact, rubbing against rough edge of damaged vessel)
Triggers release of thromboplastin enzyme & Ca2+ from platelet
Thromboplastin converts prothrombin (protein made by liver…globulin) to thrombin (needs Ca2+)
Thrombin triggers the conversion of fibrinogen (globulin) into fibrin (insoluble)
Fibrin traps blood cells (clot)

13. Antigen vs Antibody
Antigen – an agent that is foreign (or self) and is recognized by the immune system
Antibody – a Y shaped protein capable of identifying and binding to a specific antigen

14. Agglutination
Antibodies connect to the antigen of the pathogen and round up the infection in one area (a clump)

15. What’s Your Blood Type?

16. What’s Your Blood Type?

17. Can you get blood from just anyone?
Blood transfusion game