1. The Balancing Act of Neutrophils
Bart W. Bardoel, Elaine F. Kenny, Gabriel Sollberger, Arturo Zychlinsky 
Cell Host & Microbe 
Volume 15, Issue 5, Pages (May 2014)
DOI: /j.chom
Copyright © 2014 Elsevier Inc. Terms and Conditions

2. Figure 1 The Development of Neutrophils from Hematopoietic Stem Cells
Precursor development and terminal differentiation of neutrophils from hematopoietic stem cells. Essential transcription factors are highlighted in pink. HSC, hematopoietic stem cell; MPP, multipotent precursor; EMP, erythromyeloid precursor; LMP, lymphomyeloid precursor; GMP, granulocyte-macrophage precursor. Please refer to the Development of Neutrophils section for details. Adapted from Borregaard (2010).
Cell Host & Microbe  , DOI: ( /j.chom )
Copyright © 2014 Elsevier Inc. Terms and Conditions

3. Figure 2 Schematic Overview of ROS Production in the Phagosome
MPO is stored in azurophilic granules within the neutrophil. After phagocytosis, the granules fuse and release MPO into the phagosome. The NADPH oxidase complex generates superoxide that is converted into hydrogen peroxide. MPO uses hydrogen peroxide to catalyze the production of potent antimicrobial molecules, such as hypochlorous acid.
Cell Host & Microbe  , DOI: ( /j.chom )
Copyright © 2014 Elsevier Inc. Terms and Conditions

4. Figure 3 The Good and Bad Sides of Neutrophil Activation
The three main antimicrobial functions of neutrophils and their positive (green) and negative (red) aspects for the host.
Cell Host & Microbe  , DOI: ( /j.chom )
Copyright © 2014 Elsevier Inc. Terms and Conditions