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Analysis of longitudinal quality-of-life data in high-risk operable patients with lung cancer: Results from the ACOSOG Z4032 (Alliance) multicenter randomized.

Published byLinda Potter Modified over 5 years ago

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Presentation on theme: "Analysis of longitudinal quality-of-life data in high-risk operable patients with lung cancer: Results from the ACOSOG Z4032 (Alliance) multicenter randomized."— Presentation transcript:

1 Analysis of longitudinal quality-of-life data in high-risk operable patients with lung cancer: Results from the ACOSOG Z4032 (Alliance) multicenter randomized trial  Hiran C. Fernando, MD, Rodney J. Landreneau, MD, Sumithra J. Mandrekar, PhD, Francis C. Nichols, MD, Thomas A. DiPetrillo, MD, Bryan F. Meyers, MD, Dwight E. Heron, MD, Shauna L. Hillman, MS, David R. Jones, MD, Sandra L. Starnes, MD, Angelina D. Tan, BS, Benedict D.T. Daly, MD, Joe B. Putnam, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 149, Issue 3, Pages (March 2015) DOI: /j.jtcvs Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Patient CONSORT diagram. SR, Sublobar resection; SRB, SR with brachytherapy; IRB, institutional review board; NSCLC, non–small cell lung cancer; T3N0, tumor stage 3, nodal involvement; T3, tumor stage 3; CT, computed tomography; QOL, quality of life. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Comparison of quality-of-life scores at each time point, by arm. SOBQ, (University of California, San Diego) shortness of breath questionnaire; SR, sublobar resection; SF36, 36-item short-form health survey. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Kaplan-Meier curve for overall survival by median values of baseline SOBQ scores. HR, Hazard ratio; SOBQ, (University of California, San Diego) shortness of breath questionnaire; CI, confidence interval. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

5 Overall survival after sublobar resection, comparing patients with low and high baseline dyspnea scores. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2015 The American Association for Thoracic Surgery Terms and Conditions

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