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Frailty, core muscle size, and mortality in patients undergoing open abdominal aortic aneurysm repair  Jay Soong-Jin Lee, BS, Kevin He, MS, Calista M.

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Presentation on theme: "Frailty, core muscle size, and mortality in patients undergoing open abdominal aortic aneurysm repair  Jay Soong-Jin Lee, BS, Kevin He, MS, Calista M."— Presentation transcript:

1 Frailty, core muscle size, and mortality in patients undergoing open abdominal aortic aneurysm repair  Jay Soong-Jin Lee, BS, Kevin He, MS, Calista M. Harbaugh, BS, Douglas E. Schaubel, PhD, Christopher J. Sonnenday, MD, Stewart C. Wang, MD, Michael J. Englesbe, MD, Jonathan L. Eliason, MD  Journal of Vascular Surgery  Volume 53, Issue 4, Pages (April 2011) DOI: /j.jvs Copyright © 2011 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Histograms of aneurysm diameter (A) and total psoas cross-sectional area (B). The distribution of aneurysm diameter is skewed to the left, whereas total psoas area has a normal distribution with a broader range of values. AAA, Abdominal aortic aneurysm; TPA, total psoas area. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Three-year Kaplan-Meier survival curves for the tertiles of total psoas size in patients who have undergone open abdominal aortic aneurysm (AAA) repair. Sample sizes available for analysis at annual time points are included. The solid lines terminate when the SE exceeds 10%. (P = .033). Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

4 Fig 3 This figure shows the covariate-adjusted hazard ratio for mortality due to a 1000 mm2 decrease in psoas area, with the hazard ratio plotted against time. The effect of total psoas area on mortality is time-dependent. The hazard ratio (HR) due to psoas area is highest immediately after repair (HR = 4.50), then rapidly decays over time to approximately HR = 2.3 at 180 days after repair. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

5 Fig 4 Effect of total psoas area (TPA) on 90-day postoperative mortality, as quantified by the covariate-adjusted hazard ratio (HR). The reference TPA (HR = 1) is 2230 mm2, which is the median TPA in our study population. For patients differing by 1000 mm2 with respect to TPA, the patient with the higher TPA faces a postoperative mortality rate equal to 37% (HR = 0.37) of the patient with the lower TPA. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

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