1. CRISPR genome-editing: A medical revolution
James R. Butler, MD, A. Joseph Tector, MD, PhD 
The Journal of Thoracic and Cardiovascular Surgery 
Volume 153, Issue 2, Pages (February 2017)
DOI: /j.jtcvs
Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

2. Figure 1
CRISPR/Cas9 genome-editing is revolutionizing the production of model animals. This system creates targeted genome modifications by directing a nuclease (protein capable of creating double-strand breaks in DNA) to a specific genomic sequence by RNA-guided homology. Because NHEJ is an error-prone process of DNA repair, silencing mutations often are introduced. After a genetically modified cell is created, clonal model animals may be created through somatic cell nuclear transfer. NHEJ, Nonhomologous end joining.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions

3. CRISPR/Cas9 genome-editing is revolutionizing the production of model animals.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs )
Copyright © 2016 The American Association for Thoracic Surgery Terms and Conditions