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(A) Safety profile overview.

Published byAnnabella Lee Bates Modified over 5 years ago

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Presentation on theme: "(A) Safety profile overview."— Presentation transcript:

1 (A) Safety profile overview.
(A) Safety profile overview. Any grade neutropenia, any grade anaemia, any grade fatigue, any grade nausea, any grade vomiting, any grade decreased appetite, any grade headache, any grade diarrhoea and any grade palmar-plantar erythrodysesthesia in patients with BRCA-mutated HER2-negative breast cancer treated with PARPi versus those treated with monochemotherapy (controls). (B) Safety profile overview. Grade 3–4 neutropenia and grade 3–4 anaemia in BRCA-mutated HER2-negative patients treated with PARPi versus those treated with monochemotherapy (controls). (C) Treatment discontinuation rate in BRCA-mutated HER2-negative patients treated with PARPi versus those treated with monochemotherapy (controls). The size of the squares is proportional to the weight of each study. (D) Time to clinically meaningful deterioration in quality of life in patients with BRCA-mutated HER2-negative metastatic breast cancer treated with PARPi versus those treated with monochemotherapy (controls). The size of the squares is proportional to the weight of each study. PARPi, PARP inhibitors. Francesca Poggio et al. ESMO Open 2018;3:e000361 Copyright © European Society for Medical Oncology. All rights reserved.

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