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Figure 3 Gene expression in CSF cell pellets

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1 Figure 3 Gene expression in CSF cell pellets
Gene expression in CSF cell pellets Gene expression in CSF cell pellets reflecting (A.a–A.b) T cells, (B) B cells, (C.a–C.e) plasma cells, (D.a–D.b) myeloid cells, (E) T-cell activation, and (F) type I IFN response before and after opicinumab or placebo treatment. Each line connects the 2 time points of an individual patient. Patients from the 30-, 60-, and 100-mg/kg groups have been combined. Healthy range (shaded area) was determined by the minimum and maximum values of 5 healthy control patients evaluated. Ig = immunoglobulin; TCRα = T-cell receptor alpha. Ann Ranger et al. Neurol Neuroimmunol Neuroinflamm 2018;5:e417 Copyright © 2017 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.


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