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Role of the Mycobiome in Human Acute Graft-versus-Host Disease

Published byAugusto Adriano Barateiro Modified over 6 years ago

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Presentation on theme: "Role of the Mycobiome in Human Acute Graft-versus-Host Disease"— Presentation transcript:

1 Role of the Mycobiome in Human Acute Graft-versus-Host Disease
Walter J.F.M. van der Velden, Mihai G. Netea, Anton F.J. de Haan, Gerwin A. Huls, J. Peter Donnelly, Nicole M.A. Blijlevens  Biology of Blood and Marrow Transplantation  Volume 19, Issue 2, Pages (February 2013) DOI: /j.bbmt Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Incidence of acute GVHD in relation to Candida colonization. Shown are time-dependent occurrence of GVHD grade II-IV (A) and GI-GVHD (B) in patients colonized with Candida spp (green line) and patients not colonized (blue line). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Candida colonization, dectin-1 status, and GVHD. Dectin-1 single-nucleotide polymorphism Y238X resulted in significantly more Candida colonization but had no direct effect on acute GVHD grade II-IV. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

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