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Serotonin Synthesis and Uptake in Symptomatic Patients With Crohn’s Disease in Remission  Itta M. Minderhoud, Bas Oldenburg, Marguerite E.I. Schipper,

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1 Serotonin Synthesis and Uptake in Symptomatic Patients With Crohn’s Disease in Remission 
Itta M. Minderhoud, Bas Oldenburg, Marguerite E.I. Schipper, José J.M. ter Linde, Melvin Samsom  Clinical Gastroenterology and Hepatology  Volume 5, Issue 6, Pages (June 2007) DOI: /j.cgh Copyright © 2007 AGA Institute Terms and Conditions

2 Figure 1 TpH-1 mRNA expression in the colon. CD patients in remission with IBS-like (CD + IBS) symptoms show a higher TpH-1 level compared with controls (HC) (*P ≤ .005) and compared with CD patients in remission without IBS-like symptoms (CD-IBS; †P ≤ .01). Clinical Gastroenterology and Hepatology 2007 5, DOI: ( /j.cgh ) Copyright © 2007 AGA Institute Terms and Conditions

3 Figure 2 The number of (A) enteroendocrine cells and (B) EC cells per colonic gland in healthy controls (HC), CD patients in remission with IBS-like symptoms (CD + IBS), and CD patients in remission without IBS-like symptoms (CD-IBS). Values represent medians and ranges. Clinical Gastroenterology and Hepatology 2007 5, DOI: ( /j.cgh ) Copyright © 2007 AGA Institute Terms and Conditions


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