Presentation is loading. Please wait.

Presentation is loading. Please wait.

Identification of p21 inhibitors to enhance chondrogenesis in osteoarthritic synovial mesenchymal progenitor cells  K.L. Bertram, T. Irvine, P. Tailor,

Published byΦαίδρα Τρικούπης Modified over 5 years ago

Similar presentations

Presentation on theme: "Identification of p21 inhibitors to enhance chondrogenesis in osteoarthritic synovial mesenchymal progenitor cells  K.L. Bertram, T. Irvine, P. Tailor,"— Presentation transcript:

1 Identification of p21 inhibitors to enhance chondrogenesis in osteoarthritic synovial mesenchymal progenitor cells  K.L. Bertram, T. Irvine, P. Tailor, A. Narendran, R. Krawetz  Osteoarthritis and Cartilage  Volume 24, (April 2016) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1. Luminescence relative to DMSO control after 24 hr exposure to candidate p21 inhibitors.
Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2. Pellet size and SOX9 mRNA expression of MPCs following 21 days of chondrogenesis with inhibitor treatment. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © Terms and Conditions

Download ppt "Identification of p21 inhibitors to enhance chondrogenesis in osteoarthritic synovial mesenchymal progenitor cells  K.L. Bertram, T. Irvine, P. Tailor,"

Similar presentations

Full-thickness cartilage defects repaired by human induced pluripotent stem cells (IPSCS)-derived mesenchymal stem cells and plga scaffolds D. Shi, X.

Full-thickness cartilage defects repaired by human induced pluripotent stem cells (IPSCS)-derived mesenchymal stem cells and plga scaffolds D. Shi, X.
The effects of polyacrylamide hydrogel in normal and osteoarthritic animal joints  L.H. Christensen, L. Camitz, K.E. Illigen, M. Hansen, R. Sarvaa, P.G.

The effects of polyacrylamide hydrogel in normal and osteoarthritic animal joints  L.H. Christensen, L. Camitz, K.E. Illigen, M. Hansen, R. Sarvaa, P.G.
Synergistic effects of progranulin and low intensity pulsed ultrasound on chondrocyte differentiation, migration and metabolism  S.M. Uddin, B. Richbourgh,

Synergistic effects of progranulin and low intensity pulsed ultrasound on chondrocyte differentiation, migration and metabolism  S.M. Uddin, B. Richbourgh,
Pressure and inflammatory stimulation induced increase of cadherin-11 is mediated by PI3K/Akt pathway in synovial fibroblasts from temporomandibular joint 

Pressure and inflammatory stimulation induced increase of cadherin-11 is mediated by PI3K/Akt pathway in synovial fibroblasts from temporomandibular joint 
Full-thickness cartilage defects repaired by human induced pluripotent stem cells (IPSCS)-derived mesenchymal stem cells and plga scaffolds  D. Shi, X.

Full-thickness cartilage defects repaired by human induced pluripotent stem cells (IPSCS)-derived mesenchymal stem cells and plga scaffolds  D. Shi, X.
Immunomodulatory effect of mesenchymal stem cells following intra-articular injection in a model of osteoarthritis: a potential role for apoptosis  P.

Immunomodulatory effect of mesenchymal stem cells following intra-articular injection in a model of osteoarthritis: a potential role for apoptosis  P.
G.-I. Im, H.-J. Kim  Osteoarthritis and Cartilage 

G.-I. Im, H.-J. Kim  Osteoarthritis and Cartilage 
C. M. Keenan, A. Beckett, H. Sutherland, I. Prior, L. R. Ranganath, J

C. M. Keenan, A. Beckett, H. Sutherland, I. Prior, L. R. Ranganath, J
S. Gavard  Osteoarthritis and Cartilage 

S. Gavard  Osteoarthritis and Cartilage 
Gene expression profiling for confirmation of effects of DNA polymeric molecules on in vitro arthritis model  H.-J. Kim, A. Baek, M. Kim, S.-R. Cho  Osteoarthritis.

Gene expression profiling for confirmation of effects of DNA polymeric molecules on in vitro arthritis model  H.-J. Kim, A. Baek, M. Kim, S.-R. Cho  Osteoarthritis.
In vitro cell surface markers are insufficient to identify in vivo/in situ multipotent synovial mesenchymal stem cells isolated from normal or osteoarthritic.

In vitro cell surface markers are insufficient to identify in vivo/in situ multipotent synovial mesenchymal stem cells isolated from normal or osteoarthritic.
Comparative analysis with collagen type II distinguishes cartilage oligomeric matrix protein as a primary TGFβ-responsive gene  H. Li, D.R. Haudenschild,

Comparative analysis with collagen type II distinguishes cartilage oligomeric matrix protein as a primary TGFβ-responsive gene  H. Li, D.R. Haudenschild,
Prospective economic evaluation of the costs for medications and nutraceuticals in knee osteoarthritis  M. Chung, N. Zhao, J.B. Wong, C. Wang  Osteoarthritis.

Prospective economic evaluation of the costs for medications and nutraceuticals in knee osteoarthritis  M. Chung, N. Zhao, J.B. Wong, C. Wang  Osteoarthritis.
Characterization of cartilage repair in a focal mouse defect model

Characterization of cartilage repair in a focal mouse defect model
Bone shape does not cause OA – But OA does change bone shape; a study on data from 4654 knees from the Osteoarthritis Initiative  M.A. Bowes, C.B. Wolstenholme,

Bone shape does not cause OA – But OA does change bone shape; a study on data from 4654 knees from the Osteoarthritis Initiative  M.A. Bowes, C.B. Wolstenholme,
Osteoarthritis and Cartilage

Osteoarthritis and Cartilage
Human synovial fluid derived mesenchymal stem cells expanded under low oxygen conditions and in a serum-free environment exhibit enhanced lineage-specific.

Human synovial fluid derived mesenchymal stem cells expanded under low oxygen conditions and in a serum-free environment exhibit enhanced lineage-specific.
Role of endothelin-1 in endochondral ossification and osteoarthritis

Role of endothelin-1 in endochondral ossification and osteoarthritis
Mineralization of meniscal enthesis in osteoarthritic knees

Mineralization of meniscal enthesis in osteoarthritic knees
Osteoarthritis and Cartilage

Osteoarthritis and Cartilage

Similar presentations

Ads by Google