1. Nitrogen concentration curve at the end of the washout from a nitrogen multiple-breath washout measurement in a patient with primary ciliary dyskinesia with fluctuation around 2.5% analysed in LungSim (NM GmbH).
Nitrogen concentration curve at the end of the washout from a nitrogen multiple-breath washout measurement in a patient with primary ciliary dyskinesia with fluctuation around 2.5% analysed in LungSim (NM GmbH). The crosses represent the end-tidal nitrogen concentration per breath, the line indicates 2.5% of the initial nitrogen concentration. The y-axis represents the normalised nitrogen concentration (Cet) and the x-axis the cumulative expiratory volume (CEV). Lung clearance index (LCI) from the first of three consecutive breaths below the 2.5% cut-off (LCIstandard) and from the first breath below 2.5% (LCIfirst-breath) are highlighted. LCIfirst-breath is calculated seven breaths prior to LCIstandard.
Pinelopi Anagnostopoulou et al. ERJ Open Res 2018;4:
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