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Ventilator-associated pneumonia—Understanding epidemiology and pathogenesis to guide prevention and empiric therapy  Patrick Francioli, Jean Chastre,

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Presentation on theme: "Ventilator-associated pneumonia—Understanding epidemiology and pathogenesis to guide prevention and empiric therapy  Patrick Francioli, Jean Chastre,"— Presentation transcript:

1 Ventilator-associated pneumonia—Understanding epidemiology and pathogenesis to guide prevention and empiric therapy  Patrick Francioli, Jean Chastre, Martin Langer, Jose Ignacio Santos, Pramod M Shah, Antonio Torres  Clinical Microbiology and Infection  Volume 3, Pages S61-S76 (April 1997) DOI: /j tb00647.x Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

2 Figure 1 Routes of infection in ventilator-associated pneumonia
Clinical Microbiology and Infection 1997 3, S61-S76DOI: ( /j tb00647.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

3 Figure 2 Effect of anti-ulcer prophylaxis on the incidence on pneumonia. With permission of Annals of Internal Medicine 64. Clinical Microbiology and Infection 1997 3, S61-S76DOI: ( /j tb00647.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions

4 Figure 3 Summary of reported cases of nosocomial pneumonia in mechanically-ventilated patients randomized to stress bleeding prophylaxis with sucralfate (▪) versus antacids (□) and H2 blockers (□) or H2 blockers alone (▪). Adapted from Craven et al. 72. Prevention and control of nosocomial infections. Williams & Wilkins (1990). Clinical Microbiology and Infection 1997 3, S61-S76DOI: ( /j tb00647.x) Copyright © 1997 European Society of Clinical Infectious Diseases Terms and Conditions


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