1. Intrathecal lidocaine elevates prostaglandin E2 levels in cerebrospinal fluid: a microdialysis study in freely moving rats†  
V. Umbrain, L. Shi, M.-H. Lauwers, I. Smolders, Y. Michotte, F. Camu 
British Journal of Anaesthesia 
Volume 101, Issue 5, Pages (November 2008)
DOI: /bja/aen243
Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

2. Fig 1
PGE2 concentrations in CSF dialysates after i.t. injection of saline (50 μl), 400 μg lidocaine (20 μl), or 1000 μg lidocaine (50 μl). Data are reported as mean (sem) per cent change of baseline. *P<0.05 vs baseline for Lido 1000 μg; **P<0.05 for Lido 400 μg.
British Journal of Anaesthesia  , DOI: ( /bja/aen243)
Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

3. Fig 2
Effect of pretreatment with i.t. MK801 (5 μg) before i.t lidocaine 400 μg on dialysate CSF PGE2 concentrations. Data are reported as mean (sem) per cent change of baseline. *P<0.05 vs baseline.
British Journal of Anaesthesia  , DOI: ( /bja/aen243)
Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

4. Fig 3
Effect of pretreatment with i.t. SC76309A (10 μg) before i.t. lidocaine 400 μg on dialysate CSF PGE2 concentrations. Data are reported as mean (sem) per cent change of baseline. *P<0.05 vs baseline.
British Journal of Anaesthesia  , DOI: ( /bja/aen243)
Copyright © 2008 British Journal of Anaesthesia Terms and Conditions

5. Fig 4
Radiant heat sensitivity and Von Frey testing after i.t. lidocaine 400 μg. Data are reported as mean (sem) per cent change of baseline. *P<0.05 vs baseline.
British Journal of Anaesthesia  , DOI: ( /bja/aen243)
Copyright © 2008 British Journal of Anaesthesia Terms and Conditions