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Proteasome Inhibitors and Patients
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RRMM Overview
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Multiple Treatment Options Are Available for RRMM
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Proteasome Inhibitors: Key Characteristics
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ESMO Practice Guidelines: RRMM
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Type of Relapse May Influence Treatment Decisions
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Efficacy of Ixazomib in Patients With RRMM and High-Risk Cytogenetics: TOURMALINE-1 Trial
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Choice of Proteasome Inhibitor at Relapse Depends on Multiple Factors
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Patient Profile 1: Young and Fit
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Prolonged Exposure to Proteasome Inhibitors Is Associated With Improved Outcomes
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Duration of Exposure to IRd in the Phase 3 TOURMALINE-1 Trial
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Weekly vs Twice Weekly Administration of Carfilzomib in RRMM: Phase 3 ARROW Trial
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Bortezomib Maintenance Therapy Improves Depth of Response After ASCT
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Ongoing Phase 3 Trials of Ixazomib as Maintenance Therapy
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Patient Profile 2: Old and Frail
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Safety Comparison of IRd vs Rd: Phase 3 TOURMALINE-1 Trial
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Patient Profile 3: Comorbidities
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Patient Profile 4: Disease-Related Factors
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Selecting an Appropriate Treatment for the Patient With RRMM
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Closing Remarks
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Abbreviations
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Abbreviations (cont)
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