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Should We Dry the Retina Faster for Longer
Should We Dry the Retina Faster for Longer? Comparing Anatomical Outcomes in nAMD
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Program Introduction
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Relevance of Morphological Responses to anti-VEGF Treatment
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FLUID Study: OCT SRF Fluid Determination
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Outcomes in Eyes with RAP in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT)
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Results from CATT Trial: IRF
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FLUID Study: Mean Change in BCVA
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Identifying Fluid vs Degenerative Changes
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BCVA Change from Baseline to Week 96: brolucizumab vs aflibercept
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In HAWK and HARRIER, Fewer Patients on brolucizumab had IRF and/or SRF Fluid at Weeks 16, 48 and 96
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In HAWK and HARRIER, Fewer Patients on brolucizumab had sub-RPE Fluid at Weeks 16, 48 and 96
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Advantages of Using an Agent With Longer Durability (ie, brolucizumab)
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Over 75% of brolucizumab 6 mg Patients who Completed Week 48 on a q12w Interval Remained on q12w Interval until Week 96
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Patient Sustained Drying of Retina with 10 Injections (brolucizumab 6 mg) Over 2 Years After Loading Dose
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HAWK and HARRIER Demonstrated Less Disease Activity at Week 16 with brolucizumab Compared to aflibercept
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Brolucizumab Achieved Superior Reductions in CST From Baseline to Week 16 and Week 48; this Difference was Maintained at Week 96
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The LADDER Trial: Initial Study Results
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The Significance of Drying the Retina at an Early Timepoint: Panelist Viewpoints
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Long-Term Maintenance of VA Results
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5-Year CATT Results: Mean VA
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The Impact of More Durable Treatments
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Abbreviations
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