1. Volume 119, Issue 6, Pages 1496-1505 (December 2000)
Postabsorptive plasma citrulline concentration is a marker of absorptive enterocyte mass and intestinal failure in humans 
Pascal Crenn, *, Colette Coudray–Lucas, ‡, Francois Thuillier, *, Luc Cynober, ‡, Bernard Messing, * 
Gastroenterology 
Volume 119, Issue 6, Pages (December 2000)
DOI: /gast
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2. Fig. 1
Schematic diagram of one part of mitochondrial enterocyte and interorgan metabolism of amino acids, i.e., glutamine, citrulline, and arginine, with a prevailing intestinal site of metabolism. P5CS, pyrroline-5-carboxylate synthase; CPS, carbamoyl phosphate synthase; OTC, ornithine transcarbamylase.
Gastroenterology  , DOI: ( /gast )
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3. Fig. 2
Plasma citrulline concentrations in permanent intestinal failure, transient intestinal failure, and controls. Heights of histograms and bars represent mean and SD, respectively. Groups were significantly different (P < 0.05). IF, intestinal failure. n = 37 (permanent IF), n = 20 (transient IF), and n = 51 (controls).
Gastroenterology  , DOI: ( /gast )
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4. Fig. 3
Degree of correlation between plasma citrulline concentration and remnant small bowel length as evaluated on radiograph films. The regression equation is: plasma citrulline (μmol/L) = 0.23 × small bowel length (cm) (μmol/L). ●, Patients with permanent intestinal failure; ○, patients with transient intestinal failure.
Gastroenterology  , DOI: ( /gast )
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5. Fig. 4
Degree of correlation between plasma citrulline concentration and remnant small bowel length in relation with oral intake in 20 patients paired for small bowel length and type of anastomosis. High oral intake (●; hyperphagic patients) corresponded to 2.4 ± 0.6 times the resting energy expenditure including 2.2 ± 0.7 g protein/kg; low oral intake (○; normophagic patients) corresponded to 1.4 ± 0.6 times the resting energy expenditure including 1.2 ± 0.6 g protein/kg. Plasma citrulline concentration differed from one group to the other (P = 0.01). The regression equations were significantly different for the intercept: in normophagic patients, plasma citrulline (μmol/L) = 0.16 × small bowel length (cm) (μmol/L), whereas in hyperphagic patients, plasma citrulline (μmol/L) = 0.15 × small bowel length (cm) (μmol/L).
Gastroenterology  , DOI: ( /gast )
Copyright © 2000 American Gastroenterological Association Terms and Conditions