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Figure 1 Body sites of microbiota that influences atherosclerosis

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1 Figure 1 Body sites of microbiota that influences atherosclerosis
Figure 1 | Body sites of microbiota that influences atherosclerosis. Bacterial DNA detected in atherosclerotic plaques might derive from bacteria residing in the oral cavity or the gut. The description of the dominant phylum in each body habitat is based on a previous publication6. Firmicutes is the most abundant phyla in the gut and oral cavity, whereas Proteobacteria is most abundant in plaques. The methods for microbiota characterization and taxonomic profiling are described in Box 2. Specific bacterial taxa in atherosclerotic plaques are also present in the oral cavity or gut6, and altered microbial composition in the gut is associated with symptomatic atherosclerosis14. Bacteria in plaques, oral cavity, or gut might initiate or augment atherosclerosis, but causal evidence is lacking. CAD, coronary artery disease. Jonsson, A. L. & Bäckhed, F. (2016) Role of gut microbiota in atherosclerosis Nat. Rev. Cardiol. doi: /nrcardio


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