1. Quick genetics review

2. Phenotypes & Genotypes Dominant & Recessive Traits Punnett Square
Tell students that they will be applying the genetic terms they reviewed previously to some of the Harry Potter characters. If possible, display the Basic Genetic Terms Worksheet for Teachers for students to refer to as needed during the lesson.
Phenotypes & Genotypes
Dominant & Recessive Traits
Punnett Square

3. First some genetics vocabulary
See if you remember the term associated with the description:)

4. Section of DNA that codes for a proteintrait
GENE

5. version of a gene or trait
Blue eyes or brown eyes Eye color would be the trait
Allele

6. Both alleles for a trait are the same
Both alleles for a trait are the same. Either both dominant or both recessive
HOMOZYGOUS

7. Two different alleles for a trait are inherited
Heterozygous

9. Allele will only be expressed when both alleles are the same
recessive

10. Allele that will be expressed when you have at least one copy of it
Dominant

12. A persons genetic makeup, what alleles they have inherited
Ff FF ff
Genotype

13. The trait that is being expressed. Observable, physical appearance
Phenotype

14. Now some concept review...

15. transcription and translation
The “Central Dogma”
Flow of genetic information in a cell
How do we move information from DNA to proteins?
transcription
translation
DNA
RNA
protein
trait
To get from the chemical language of DNA to the chemical language of proteins requires 2 major stages:
transcription and translation
replication

16. Post transcriptional modification
Introns: not expressed/ in between the coding regions Exons: Expressed

17. We will be looking at the PV92 locus on YOUR chromosome 16

18. And the ALU insert on this chromosome...
The ALU sequence is inserted at different locations throughout the chromosome, in this case it does not have effect on the persons phenotype because it is removed before expression. This insert is a SINE, small repetitive interspaced element, we don’t know what its purpose is at this point BUT we can use it to study evolutionary relationships, population genetics, establish paternity, and identify suspects.

19. You either have the insert or you don’t...
PV92 , 641 base pairs (bp)
PV92 (641bp)+ Alu insert (300bp)

20. BUT you get two versions of every gene...
One from mom and one from dad so you can either be
Homozygous (+/+ or -/-)
Heterozygous (+/-)
LET’S FIND OUT!!!