1. DNA Replication

2. DNA Replication Replication = DNA copies itself exactly
(Occurs within the nucleus)
Must do this before a cell can divide so both cells will then have identical copies of DNA
Any mistake in copying = mutation
DNA mutation = chromosomal mutation

3. A. Basic Facts of DNA Replication
1. Complementary base pairing
makes replication possible
C - G
A - T

4. A. Basic Facts of DNA Replication
2. One side of DNA molecule is a
template
for
making
the
other side (strand)
?’s 1-3

5. B. Process of DNA Replication
Uncoil & unzip DNA molecule
Enzyme HELICASE breaks weak Hydrogen Bond between bases
This happens at the REPLICATION FORK

6. B. Process of DNA Replication
2. Enzyme DNA POLYMERASE brings in complementary Nitrogenous bases/new nucleotides
DNA Polymerase

7. LIGASE puts the strands back together
C - G
A - T

8. Enzyme Review 1st Helicase=unwinds and breaks the bonds
2nd DNA Polymerase=Brings new bases and nucleotides
3rd Ligase=bonds the strands back together

9. C. Semi-conservative replication
Each new DNA molecule
contains
one old strand
&
one new strand

10. End Product of DNA Replication