1. Obesity and Weight Loss: How Can Cross-Functional Collaboration and Integrated Care Work in Practice?

3. Introduction/Overview

4. WHO Statistics on Obesity

5. The Global Social Burden of Obesity

6. Obesity Is Associated With Multiple Comorbidities

7. Life Expectancy Decreases as BMI Increases

8. Weight Loss Improves Obesity-Related Comorbidities

9. Mechanisms of Obesity Leading to CV Disease: Lipid Overflow

10. Psychosocial Burden of Obesity: Key Points

11. Obesity Is a Major Risk Factor for NAFLD

12. Obesity and Cancer: Survivability Issues

13. What Does the Primary Care Physician (and the Patient) Need to Know About Obesity?

14. Multiple Hormonal Signals Interpreted by the Central Nervous System Influence Appetite

15. Weight Loss Is a Challenge Because, Physiologically, it Is Perceived as a Dysfunction

16. Influences on Food Purchase/Consumption

17. Importance of Developing Good Eating Habits

18. Obesity Is a Disease; a Chronic Condition

19. Evidence-Based Model for Associations Between Psychiatric Disorders and Obesity

20. Tips for the Busy Clinician

21. Chronic Care Management of Patients With Obesity: the Multidisciplinary Team

22. The Multidisciplinary Team Has to Work Together

23. The Challenges and Rewards of Treating the Patient With Obesity

24. Integrated Theory of Health Behavioral Change

25. Available Weight Loss Agents

26. Orlistat-Induced Weight Loss and Maintenance at 1 Year

27. SCALE: Change in Body Weight (%), Liraglutide 3.0 mg vs Placebo

28. SCALE Maintenance (Liraglutide 3
SCALE Maintenance (Liraglutide 3.0 mg): Proportion of Patients Maintaining Run-In Weight Loss or Regaining ≥ 5% From Randomization to Week 56

29. Percentage Weight Loss From Baseline for the Modified ITT-LOCF Population and the Completer Population: Naltrexone + Bupropion vs Placebo

30. Pharmacotherapy + Diet and Exercise: Patient Selection

31. Summary and Conclusions

32. Abbreviations