1. The CaptureSMB process principle
Maximizing the efficiency of affinity capture steps
Click to proceed

2. CaptureSMB process principle
Loading of a batch column
With CaptureSMB
feed
unused resin capacity
elution
feed
fully loaded column
presentation progress

3. Contichrom and CaptureSMB explained

4. Contichrom and CaptureSMB explained
Feed
Wasted resin capacity
in batch chromatography
Internal
concentration t3 t2
Feed t1
column length

5. Contichrom and CaptureSMB explained
Feed
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.

6. Contichrom and CaptureSMB explained
Feed
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.

7. Contichrom and CaptureSMB explained
Wash
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.

8. Contichrom and CaptureSMB explained
Elution
Feed
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.
Product

9. Contichrom and CaptureSMB explained
CIP &
Re-equilibration
Feed
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.

10. Contichrom and CaptureSMB explained
Feed
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.

11. Contichrom and CaptureSMB explained
Wash
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.

12. Contichrom and CaptureSMB explained
Feed
Elution
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.
Product

13. Contichrom and CaptureSMB explained
Feed
CIP & re-equil.
Step 1:
Feed & wash
Step 2:
elute product
feed column
Step 3:
CIP & re-equil.
Start over

14. Overview CaptureSMB