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Reliability Assurance of Detection of EML4-ALK Rearrangement in Non–Small Cell Lung Cancer: The Results of Proficiency Testing in China  Yulong Li, MD,

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Presentation on theme: "Reliability Assurance of Detection of EML4-ALK Rearrangement in Non–Small Cell Lung Cancer: The Results of Proficiency Testing in China  Yulong Li, MD,"— Presentation transcript:

1 Reliability Assurance of Detection of EML4-ALK Rearrangement in Non–Small Cell Lung Cancer: The Results of Proficiency Testing in China  Yulong Li, MD, Rui Zhang, PhD, Rongxue Peng, MD, Jiansheng Ding, MD, Yanxi Han, MD, Guojing Wang, PhD, Kuo Zhang, PhD, Guigao Lin, PhD, Jinming Li, PhD  Journal of Thoracic Oncology  Volume 11, Issue 6, Pages (June 2016) DOI: /j.jtho Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

2 Figure 1 The distribution of laboratories with different methodologies and reagents. (A) Distribution of laboratories with different methods; (B) distribution of laboratories with different reagents in quantitative reverse transcriptase polymerase chain reaction (RT-PCR); (C) distribution of laboratories with different reagents in fluorescent in situ hybridization (FISH); (D) distribution of laboratories with different reagents in next-generation sequencing (NGS); and (E) distribution of laboratories with different reagents in immunohistochemical (IHC) analysis. EML4, echinoderm microtubule associated protein like 4 gene; ALK, anaplastic lymphoma receptor tyrosine kinase gene; LDT, laboratory-developed test. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

3 Supplementary Figure 1 The results of samples validation. A 1-5 are the FISH results in 1000× view of ALK 01-05, respectively. B 1-5 are the IHC results in 400× view of ALK 01-05, respectively. The detection is in controls but the results of negative and positive controls were not listed. Journal of Thoracic Oncology  , DOI: ( /j.jtho ) Copyright © 2016 International Association for the Study of Lung Cancer Terms and Conditions

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