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Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients  Justin Saunders, MD, Vijay Nambi, MD, Kay T.

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Presentation on theme: "Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients  Justin Saunders, MD, Vijay Nambi, MD, Kay T."— Presentation transcript:

1 Variability and persistence of aspirin response in lower extremity peripheral arterial disease patients  Justin Saunders, MD, Vijay Nambi, MD, Kay T. Kimball, PhD, Salim S. Virani, MD, Joel D. Morrisett, PhD, Alan B. Lumsden, MD, Christie M. Ballantyne, MD, Jing-Fei Dong, MD, PhD  Journal of Vascular Surgery  Volume 53, Issue 3, Pages (March 2011) DOI: /j.jvs Copyright © 2011 Society for Vascular Surgery Terms and Conditions

2 Fig 1 Proportion of responders (light gray), Initial Poor Responders (PRs) (darker gray), and Persistent PRs (gray stripe) are depicted. Numbers listed within each bar refer to number of subjects in that category. N = 80 total for arachidonic acid (AA)-aggregometry and adenosine diphosphate (ADP)-aggregometry; N = 71 total for Platelet Function Analyzer (PFA)-100 Epi. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2011 Society for Vascular Surgery Terms and Conditions

3 Fig 2 Venn diagram of the overlap in classification of Persistent Poor Responders (PRs) by the three assays tested. The numbers within the circles represent the numbers of subjects satisfying criteria for persistent PR by the particular assay. Subjects who satisfied two definitions of persistent PR are in the overlapping areas of the circles. One subject satisfied all three criteria for Persistent PR and is shown in the overlap of all three circles. Journal of Vascular Surgery  , DOI: ( /j.jvs ) Copyright © 2011 Society for Vascular Surgery Terms and Conditions


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