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Rosai-Dorfman disease with a concurrent mantle cell lymphoma

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1 Rosai-Dorfman disease with a concurrent mantle cell lymphoma
Alexandra Edelman, MD, Brittany Patterson, BS, Kristen Donovan, MD, Janine Malone, MD, Jeffrey Callen, MD  JAAD Case Reports  Volume 5, Issue 1, Pages (January 2019) DOI: /j.jdcr Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Patient observed initially (A) and 5 months after consolidation therapy (B). JAAD Case Reports 2019 5, 40-43DOI: ( /j.jdcr ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 A, Biopsy findings show a diffuse infiltrate of mononuclear cells with abundant pale cytoplasm in the papillary dermis. B, On higher power, histiocytes with abundant cytoplasm and conspicuous nucleoli (red arrows) and emperiopolesis of lymphocytes and neutrophils (black arrows) are seen. C, S100+ staining of histiocytes. D, Higher-power view of S100+ histiocytes with negative staining of intracytoplasmic hematolymphoid cells (arrows). JAAD Case Reports 2019 5, 40-43DOI: ( /j.jdcr ) Copyright © 2018 American Academy of Dermatology, Inc. Terms and Conditions


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