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Low Levels of Interleukin-1 Receptor Antagonist (IL-1RA) Predict Engraftment Syndrome after Autologous Stem Cell Transplantation in POEMS Syndrome and.

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Presentation on theme: "Low Levels of Interleukin-1 Receptor Antagonist (IL-1RA) Predict Engraftment Syndrome after Autologous Stem Cell Transplantation in POEMS Syndrome and."— Presentation transcript:

1 Low Levels of Interleukin-1 Receptor Antagonist (IL-1RA) Predict Engraftment Syndrome after Autologous Stem Cell Transplantation in POEMS Syndrome and Other Plasma Cell Neoplasms  Alla Keyzner, Anita D'Souza, Martha Lacy, Morie Gertz, Suzanne Hayman, Francis Buadi, Shaji Kumar, David Dingli, Ann Engebretson, Caili Tong, Angela Dispenzieri  Biology of Blood and Marrow Transplantation  Volume 19, Issue 9, Pages (September 2013) DOI: /j.bbmt Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Higher pretransplantation and posttransplantation IL-13 levels correlated with delayed neutrophil engraftment. The y-axis represents IL-13 levels, and the x-axis represents days, with day 0 being transplantation day. The black horizontal line represents the normal human levels of IL-13. All patients without delayed neutrophil engraftment (top) had undetectable IL-13 levels, whereas the majority of patients with delayed neutrophil engraftment (bottom) had significantly elevated IL-13 levels. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions


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