1. NMDA-Receptor Activation Induces Calpain-Mediated b-Catenin Cleavages for Triggering Gene Expression
Kentaro Abe et al., Cell, (2007)

2. NEURONAL ACTIVITY
- REGULATION OF DENDRITIC BRANCH STABILITY BY NEURONAL ACTIVITY
- ACTIVITY-DEPENDENT MODULATION OF LOCAL CYTOSKELETON AND ADHESION MOLECULES
- REGULATION OF DENDRITIC DEVELOPMENT BY ACTIVITY DEPENDENT GENE EXPRESSION
뉴런은 일반 셀들과 다른 여러가지 특징들이 존재하는데, 그중에 대표적인 것이 뉴런날 엑티비티가 존재하
이런 뉴런의
Chen Y et al., J Neurobiol, (2005)

3. LTP ( long-terrm potentiation)
Memory formation
Chen Y et al., J Neurobiol, (2005)

4. NMDA (N-methyl-D-aspartate) receptor
Cooke SF et al., Brain, (2006)

5. Calpain (calcium-dependent, non-lysosomal cysteine protease)
Franco SJ et al., J Cell Sci (2005)

6. Calpain regulates cell migration
Franco SJ et al., J Cell Sci (2005)

7. Motility-related calpain substrates of Calpain
Franco SJ et al., J Cell Sci (2005)

8. Activity-Dependent Cleavages of b-Catenin by Calpain
AVP : NMDA-R antagonist
CNQX : AMPA-R antagonist
MCPG : mGluR antagonist
MDL28170 : calpain inhibitor

9. Activity-Dependent Cleavages of b-Catenin by Calpain
MDL28170 : calpain inhibitor

10. Nuclear Translocation of Cleaved b-Catenin Fragments
AVP : NMDA-R antagonist CNQX : AMPA-R antagonist
MCPG : mGluR antagonist MDL28170 : calpain inhibitor

11. Activation of Tcf-Dependent Gene Transcription by the b-Catenin Fragments
AVP : NMDA-R antagonist, MDL28170 : calpain inhibitor

12. Activation of Tcf-Dependent Gene Transcription by the b-Catenin Fragments
MDL28170 : calpain inhibitor

13. Activation of Tcf-Dependent Gene Transcription by the b-Catenin Fragments

14. Calpain-Dependent b-Catenin Cleavage and Tcf Activation In Vivo