Download presentation
Presentation is loading. Please wait.
Published byHarry Benson Modified over 5 years ago
1
De novo autoimmune hepatitis after liver transplantation
Giorgina Mieli-Vergani, Diego Vergani Journal of Hepatology Volume 40, Issue 1, Pages 3-7 (January 2004) DOI: /j.jhep
2
Fig. 1 De novo autoimmune hepatitis post liver transplant. (A) Chronic hepatitis with moderate portal and interface mononuclear cell infiltrate, including plasma cells (haematoxilyn-eosin staining); (B) reticulin staining showing bridging collapse, a lesion resulting from extensive death of hepatocytes and consequent coalescence of the supportive structure (histological pictures kindly provided by Professor Bernard Portmann). Journal of Hepatology , 3-7DOI: ( /j.jhep )
3
Fig. 2 (A) Heart transplant from an allogeneic mouse results not only in rejection, but also in the production of antibodies and CD4 T cells directed against cardiac myosin in the recipient. (B) Transplant of allogeneic skin or of a syngeneic heart do not lead to cardiac-specific autoimmunity, indicating that this response is tissue-specific and that an allogeneic response is necessary to break tolerance to cardiac myosin. Journal of Hepatology , 3-7DOI: ( /j.jhep )
Similar presentations
© 2025 SlidePlayer.com. Inc.
All rights reserved.