1. DNA Transcription / Translation
Jeopardy!

2. During translation, what molecule brings amino acids to the ribosome?

3. Ribosomes are made of
A. Protein
B. rRNA
C. tRNA
D. rRNA and Protein

4. Label this

5. What is produced once transcription is completed?

6. What is added to the mRNA during processing before it leaves the nucleus?

7. What is the purpose of tRNA?

8. Sickle Cell anemia is caused by what type of mutation?
A. Substitution
B. Insertion
C. Deletion
D. Frameshift

9. What is a codon for Arginine?
A. AGC
B. TAC
C. AGC
D. CGC

10. Transcribe this sequence: CTATCGG
A. CUAUCGG
B. CATAGCC
C. GAUAGCC
D. CCGAUAG

11. During Elongation of translation, what happens with the arrival of each new tRNA?
A. New ribosomes attach
B. New tRNA’s bind to Esite
C. Peptide is passed from tRNA in Psite to Asite
D. Peptide is passed from tRNA in Psite to Esite.

12. Amino acids are bound by a ______ bond.

13. What is the purpose of mRNA?

14. What is a nonsense mutation?

15. Transcription begins when RNA polymerase…
A. attaches to the initiator sequence of a gene
B. unwinds a strand of DNA.
C. binds to a strand of RNA.
D. attaches to the promoter sequence of a gene.

16. Protein synthesis continues until
A. A stop codon is reached
B. The termination sequence is reached
C. The amino acid sequence runs out
D. The end of the sequence is reached

17. What is a chain of amino acids is called?

18. DNA is replicated from CCTAATA to CCTATA
DNA is replicated from CCTAATA to CCTATA. What type of mutation occurred?

19. If DNA codons are BAT BAT BAT and an andenine base is added in the beginning, which would be a result?
A. A BAT BAT BAT
B. ABA TBA TBA T
C. Frameshift
D. B and C
None of the above

20. If AUG is the codon, what is the anticodon?

21. What happens during transcription?
A. RNA polymerase moves along the DNA strand that is oriented in the 5’ to 3’ direction.
B. RNA polymerase must first bind to a promoter sequence.
C. Transcription is always initiated at the start codon.
D. The 3’ end of the RNA molecule is produced first.

22. Label this

23. A segment of DNA that codes for a protein is known as

24. What process forms peptide bonds?

25. How many water molecules are produced from 260 Amino Acids?

26. A genetic mutation that only affects one type of amino acid is known as a __________ mutation.

27. Label this

28. Remove the intron (AUA) from the following DNA sequence. ACTATAGAT
A. ACTACAGAT
B. ACTGAT
C. UGAUAUCAU
D. UGUCUA

29. Translate the following sequence… UCAAGU
A. methionine -tyrosine
B. methionine-serine
C. serine-serine
D. Isoleucine - Valine

30. What site on the ribosome allows tRNA’s to attach to the mRNA strand?
A. A Site
B. P Site
C. E Site
D. C Site

31. Where does translation occur?

32. What does the r in rRNA stand for?

33. What is the DNA strand that made this mRNA strand? AUCCAU
A. ATCCAT
B. AUGGAT
C. TAGGTA
D. ATGGAT

34. What are the sections of mRNA that code for a protein called?

35. What process is pictured below?

36. UAA is a codon for

37. The anticodon CAG codes for which amino acid?
A. Glutamine
B. Serine
C. Leucine
D. Valine
E. None

38. Where would a DNA substitution probably have the smallest or least effect on the organism?
A. Exon
B. Histone
C. Intron
D. Operon

39. At the very beginning of translation, the first tRNA molecule binds to what site on the ribosome?

40. What part of the mRNA binds to the ribosome?
A. 3’ End
B. 5’ End
C. Poly A Tail
D. Exons

41. Double Jeopardy
If the original amino acid sequence was supposed to be: Met- Arg-Ser-Val-Stop, but instead was Met-Arg-Stop. What type of mutation occurred? Would this affect the protein? If so, in what way? Find the DNA sequence for this protein: MET- Tyrosine- Lysine- Arginine- Stop

42. Double Jeopardy
5’ A C G A A A T A C A G A C A T A T T 3’