1. Change from baseline in (A) E-RS total score and (B) E-RS cough and sputum domain score over the study period in ATTAIN and the active-comparator study.
Change from baseline in (A) E-RS total score and (B) E-RS cough and sputum domain score over the study period in ATTAIN and the active-comparator study. Data are reported as LS mean+SE. E-RS total score ranged from 0 to 40; E-RS cough and sputum domain score ranged from 0 to 11. Higher scores indicate more severe symptoms. *p<0.05, **p<0.01, ***p<0.001 vs placebo. E-RS, Evaluating Respiratory Symptoms, formerly known as EXAcerbations of Chronic pulmonary disease Tool; LS, least squares; MCID, minimum clinically important difference.
Lorcan McGarvey et al. BMJ Open Resp Res 2016;3:e000148
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