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Lung Cancer with Localized Ground-Glass Attenuation Represents Early-Stage Adenocarcinoma in Nonsmokers Nobuhiko Seki, MD, Shigeki Sawada, MD, Masao Nakata, MD, Takeshi Inoue, MD, Rieko Nishimura, MD, Yoshihiko Segawa, MD, Reishi Shibakuki, MD, Kenji Eguchi, MD Journal of Thoracic Oncology Volume 3, Issue 5, Pages (May 2008) DOI: /JTO.0b013e31816a4994 Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions
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FIGURE 1 Transverse thin-section computed tomography images of lung adenocarcinoma. Tumors were classified into four groups according to semiquantitatively calculated GGA ratios. (A) 100% GGA ratio tumor, (B) 99–50% GGA ratio tumor, (C) 49–1% GGA ratio tumor, and (D) 0% GGA ratio tumor. Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31816a4994) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions
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FIGURE 2 Patient flow. CT, computed tomography.
Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31816a4994) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions
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FIGURE 3 Relapse-free survival curves stratified by both GGA ratio and clinical stage. The 5-year relapse-free survival rate of patients with stage IA disease (n = 55) or stage IB disease (n = 10) was highest (100%) when the GGA ratio was ≥50%. When the GGA ratio was 49–1%, the 5-year relapse-free survival rate of patients with stage IA disease (n = 35; 95.5%) was significantly greater than that of patients with stage IB disease (n = 14; 61.9%, p = 0.047). Similarly, when the GGA ratio was 0%, the 5-year relapse-free survival rate of patients with stage IA disease (n = 81; 67.7%) was significantly greater than that of patients with stage IB disease (n = 30; 54.6%, p = 0.019). Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e31816a4994) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions
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