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Figure 2 7T MRI can differentiate between early PML and MS lesions Two different patterns of brain lesions were observed using 7T MRI: ring-enhancing lesions.

Published byHinrich Messner Modified over 5 years ago

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Presentation on theme: "Figure 2 7T MRI can differentiate between early PML and MS lesions Two different patterns of brain lesions were observed using 7T MRI: ring-enhancing lesions."— Presentation transcript:

1 Figure 2 7T MRI can differentiate between early PML and MS lesions Two different patterns of brain lesions were observed using 7T MRI: ring-enhancing lesions (black arrows, D) reveal central intralesional veins characteristic for multiple sclerosis (MS) plaques (white arrows, C) and perilesional edema (black asterisks, C) on T2*-weighted imaging. 7T MRI can differentiate between early PML and MS lesions Two different patterns of brain lesions were observed using 7T MRI: ring-enhancing lesions (black arrows, D) reveal central intralesional veins characteristic for multiple sclerosis (MS) plaques (white arrows, C) and perilesional edema (black asterisks, C) on T2*-weighted imaging. Additionally, small punctate lesions (oval, C) were present on T2*-weighted imaging. These microcystic lesions developed into confluent progressive multifocal leukoencephalopathy (PML) lesions over time (E), and may thus represent earliest PML stages. In contrast, punctate lesions were barely visible on the initial 1.5T T2-weighted images on day 1 (A). Volumetric interpolated brain examination (VIBE)–gad: GDTPA-enhanced 7T VIBE. (A, B) 1.5T MRI (day 1). (C, D) 7T MRI (day 4). (E) 3T fluid-attenuated inversion recovery (day 24). Tim Sinnecker et al. Neurol Neuroimmunol Neuroinflamm 2015;2:e171 © 2015 American Academy of Neurology

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